Publications

  1. Allison, J.G., P.M. Das, J. Ma, F.M. Inglis, and F.E. Jones. 2011. The ERBB4 intracellular domain (4ICD) regulates gene expression in hippocampal cells. Neuroscience Research 70:155-163.
  2. Cittelly, D.M., N.S. Spoelstra, S.M. Edgerton, J.K. Richer, A.D. Thor, and F.E. Jones. 2010. Suppression of miR-342 expression contributes to anti-estrogen resistance in breast tumor cells. Molecular Cancer 9:317.
  3. Cittelly, D.M., P.M. Das, V.A. Salvo, J.P. Fonseca, M.E. Burow, and F.E. Jones. 2010. Oncogenic HER2D16 suppresses miR-15a/16 and deregulates BCL-2 to promote endocrine resistance of breast tumors. Carcinogenesis 31:2049-2057.
  4. Das, P.M., A.D. Thor, S.M. Edgerton, S.K. Barry, D.F. Chen, and F.E. Jones. 2010. Reactivation of epigenetically silenced HER4/ERBB4 results in apoptosis of breast tumor cells. Oncogene 29:5214-5219.
  5. Rokicki, J., P.M. Das, J.M. Giltnane, O. Wansbury, A. Naresh, D.L. Rimm, B.A. Howard, and F.E. Jones. 2010. The ERa coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium. Molecular Cancer  9:150.
  6. Thor, A.D., S.M. Edgerton, and F.E. Jones. 2009. Subcellular localization of the HER4 intracellular domain, 4ICD, identifies distinct prognostic outcomes for breast cancer patients. The American Journal of Pathology 175:1802-1809.
  7. Mitra, D., M.J. Brumlik, S.U. Okamgba, T.T. Tyson, J. Parvani, E. Brogi, and F.E. Jones. 2009. An oncogenic isoform of HER2 promotes metastatic breast cancer and trastuzumab resistance. Molecular Cancer Therapeutics 8:2152-2162. Received "Editor Highlight" honors.
  8. Naresh, A., A.D. Thor, S.M. Edgerton, K.C. Torkko, R. Kumar, and F.E. Jones. 2008. The HER4/4ICD estrogen receptor coactivator and BH3-only protein is an effector of tamoxifen-induced apoptosis. Cancer Research 68:6387-6395. Received journal cover honors.
  9. Gullick, W.J. and F.E. Jones. 2008. The epidermal growth factor family of ligands and receptors grows and grows. Journal of Mammary Gland Biology and Neoplasia 13:157.
  10. Jones, F.E. 2008. HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer. Journal of Mammary Gland Biology and Neoplasia 13:247-258. Received journal cover honors.
  11. Kirkegaard, T., A. Naresh, V.S. Sabine, S.M. Tovey, J. Edwards, B. Dunne, T.G. Cooke, F.E. Jones*, and J.M.S. Bartlett*. 2008. Expression of tumor necrosis factor-a converting enzyme (TACE) in endocrine cancers. American Journal of Clinical Pathology 129:735-743. *Indicates shared corresponding authors.
  12. Vidal, G.A., D.E. Clark, L. Marrero, and F.E. Jones. 2007. A constitutively active ERBB4/HER4 mutant with enhanced apoptotic and transcriptional co-activation activities. Oncogene 26:462-466.
  13. Zhu, Y., L.L. Sullivan, S.S. Nair, C.C. Williams, A. Pandy, L. Marrero, R.K. Vadlamudi, and F.E. Jones. 2006. Coregulation of estrogen receptor by estrogen-inducible ERBB4/HER4 establishes a growth promoting autocrine signal in breast cancer. Cancer Research 66:7991-7998.
  14. Naresh, A., W. Long, G.A. Vidal, A., W.C. Wimley, L. Marrero, C.I. Sartor, S. Tovey, T.G. Cooke, J.M.S. Bartlett, and F.E. Jones. 2006. The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells. Cancer Research66:6412-6420.
  15. Clark, D.E., C.C. Williams, T.T. Duplessis, K.L. Moring, A.R. Notwick, W.S. Lane, I. Beuvink, N.E. Hynes, and F.E. Jones. 2005. ERBB4/HER4 potentiates STAT5A transcriptional activity by regulating novel STAT5A serine phosphorylation events. The Journal of Biological Chemistry. 280: 24175-24180.
  16. Vidal, G.A., A. Naresh, L. Marrero, and F.E. Jones. 2005. Presenilin-dependent g-secretase processing regulates multiple ERBB4/HER4 activities. The Journal of Biological Chemistry. 280:19777-19783.
  17. Williams, C.C., J.G. Allison, G.A. Vidal, M.E. Burow, B.S. Beckman, L. Marrero, and F.E. Jones. 2004. The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone. The Journal of Cell Biology 167:469-478. Received journal cover honors.
  18. Zhu, Y. and F. E. Jones. 2004. Expression and activation of ErbB signaling in the mouse prostate. The Prostate 60:68-75.
  19. Jones, F. E., Golding, J. P., and Gassmann, M. 2003. ErbB4 signaling during breast and neural development: Novel genetic models reveal unique ErbB4 activities. Cell Cycle  2:61-65.
  20. Long, W., K.-W. Wagner, K. C. K. Lloyd, N. Binart,  J. M. Shillingford, L. Hennighausen, and F. E. Jones. 2003. Impaired differentiation and lactational failure in ErbB4-deficient mammary glands identify ErbB4 as an obligate mediator of Stat5. Development 130:5257-5268.
  21. Jones, F. E., Burow, M. E. and Hill, S. M. 2003. Signal transduction in breast cancer: silencing the cross-talk. Eur. Biopharmaceutical Rev. Spring:70-73.
  22. Li, L., S. Cleary, M. Mandarano, C. Birchmeier, and F. E. Jones. 2002. The breast proto-oncogene, HRGa regulates epithelial proliferation and lobuloalveolar functional development in the mouse mammary gland. Oncogene 21:4900-4907.