57) Qu, X.; Lin, Z.; Jayawickramarajah, J.; Alsager, J. S.; Schmidt, E.; Nephew, K. P.; Fang, F.; Balasubramanian, S.; Shan, B. G-quadruplex is critical to epigenetic activation of the lncRNA HOTAIR in cancer cells. iScience, 2023, 26, 108559 DOI:1016/j.isci.2023.108559.
56) Zarandi, M. A.; Pathak, P.; Beltrami, N.; Zhang, F.; Walker, J. N.; Brodbelt, J. S. Schmehl, R.; Jayawickramarajah, J. Heteromeric guanosine (G)-quadruplex derived antenna modules with directional energy transfer. Nanoscale, 2023, 15, 19069-19073. DOI:10.1039/d3nr04086k.
55) Yousefi, H.; Khosla, M.; Lauterboeck, L.; Okpechi, S. C.; Worthylake, D.; Garai, J.; Zabaleta, J.; Guidry, J.; Zarandi, A. M.; Wyczechowska, D.; Jayawickramarajah, J.; Yang, Q.; Kissil, J.; Alahari, S. K. A combination of novel NSC small molecule inhibitor along with doxorubicin inhibits proliferation of triple-negative breast cancer through metabolic reprogramming. Oncogene, 2022, 41, 5076-5091, DOI: 10.1038/s41388-022-02497-2.
54) Kankanamalage, D. V. D. W.; Tran, J. H. T.; Beltrami, N.; Meng, K.; Zhou, X.; Pathak, P.; Isaacs, L,; Burin, A. L.; Ali, M. F.; Jayawickramarajah, J. DNA strand displacement driven by host-guest interactions. J. Am. Chem. Soc. 2022, 144, 16502-16511, DOI:10.1021/jacs.2c05726.
53) Mackin, R.; Edwards, J. V.; Atuk, E. B.; Beltrami, N.; Condon, B. D.; Jayawickramarajah, J.; French, A. D. Structure/function analysis of truncated amino-terminal ACE2 peptide analogs that bind to SARS-Cov-2 spike glycoprotein. Molecules 2022, 27 (7), 2070. DOI:10.3390/molecules27072070.
52) Pathak, P.; Zarandi, M. A.; Zhou, X.; Jayawickramarajah, J. Synthesis and applications of porphyrin-biomacromolecule conjugates. Front. Chem. 2021, 9, 764137. DOI: 10.3389/fchem.2021.764137
51) Pandey, S.; Xiang, Y.; Kankanamalage, D.; Jayawickramarajah, J.; Leng, Y., Mao, H. Measurement of Single-Molecule Forces in Cholesterol and Cyclodextrin Host-guest complexes. J. Phys. Chem. B., 2021, 125 (40), 11112-11121. DOI:10.1021/acs.jpcb.1c03916.
50) Nawagamuwage, S. U.; Qasim, L. N.; Zhou, X.; Leong, T. X.; Parshin, I. V.; Jayawickramarajah, J.; Burin, A.; Rubtsov, I. Competition of several energy-transport initiation mechanisms defines the Ballistic transport speed. J. Phys. Chem. B, 2021, 125 (27), 7546–7555. DOI:10.1021/acs.jpcb.1c03986.
49) Bhattarai, N.; Wang, J.; Nguyen, D.; Yang, X.; Helmers, L.; Paruch, J.; Li, L.; Zhang, Y.; Meng, K.; Wang, A.; Jayawickramarajah, J.; Wang, B.; Zeng, S.; Lu, H. Nanoparticle encapsulation of non-genotoxic p53 activator inauhzin-C for improved therapeutic efficacy. Theranostics. 2021, 11, 7005-7017. doi:10.7150/thno.57404.
48) Schmidt, E.; Vik, R.; Brubaker, B. W.; Abdulahad, S. S.; Soto-Olson, D. K.; Monjure, T. A.; Battle, C. H.; Jayawickramarajah, J. Increasing student interest and self-efficacy in STEM by offering a service-learning chemistry course in New Orleans. J. Chem. Educ. 2020, 97, 11, 4008-4018. DOI:10.1021/acs.jchemed.9b01140.
47) Pandey, S.; Kankanamalage, D.; Zhou, X.; Hu, C.; Isaacs, L,; Jayawickramarajah, J.; Mao, H. Chaperone assisted host-guest interactions revealed by single-molecule force spectroscopy. J. Am. Chem. Soc. 2019. 141, 18395-18389. DOI:10.1021/jacs.9b09019.
46) Gee, A.; Grennell, J. A.; Sitaula, S.; Jayawickramarajah, J.; Ali, M. F. Flavin binding allosteric aptamer with noncovalent labeling for miR sensing. Bioconjugate Chem. 2019, 30, 2822-2827. DOI:10.1021/acs.bioconjchem.9b00561.
45) Pathak, P.; Yao, W.; Hook, K. D.; Vik, R.; Winnerdy, F. R.; Brown, J. Q.; Gibb, B. C.; Pursell, Z F.; Phan, A. T.; Jayawickramarajah, J. Bright G-quadruplex nanostructures functionalized with porphyrin lanterns. J. Am. Chem. Soc. 2019, 141, 12582-12591. DOI: 10.1021/jacs.9b03250.
44) Qasim, L.; Atuk, E. B.; Maksymov, A.; Jayawickramarajah, J.; Burin, A.; Rubtsov, I. Ballistic transport of vibrational energy through an amide group bridging alkyl chains. J. Phys. Chem. C, 2019, 123 (6), 3381–3392. DOI: 10.1021/acs.jpcc.8b11570.
43) Zhou, X.; Pathak. P.; Jayawickramarajah, J. Design, synthesis, and applications of DNA-macrocyclic host Conjugates. Chem Comm. 2018, 54, 11668-11680. DOI: 10.1039/c8cc06716c.
42) Varner, C.; Zhou, X.; Leger, J. D.; Jayawickramarajah, J.; Rubtsov, I. V. Azido alkanes as convenient reporters for mobility within lipid membranes. Chemical Physics 2018, 512, 20-26. DOI: 10.1016/j.chemphys.2018.05.020.
41) Aryal, G.; Vik, R.; Khaleel, A.; Hunter, K.; Liming, H.; Jayawickramarajah, J.; Nau, W. Structural effects on guest binding in cucurbit[8]uril-perylene monoimide host-guest complexes. ChemistrySelect 2018, 3, 4699-4704. DOI: 10.1002/slct.201800696.
40) Zhou, X.; Su, X.; Pathak, P.; Vik, R.; Vinciguerra, B.; Isaacs, L.; Jayawickramarajah, J. Host-Guest tethered DNA transducer: ATP fueled release of a protein inhibitor from cucurbit[7]uril. J. Am. Chem. Soc. 2017, 139, 13916-13921. DOI: 10.1021/jacs.7b07977.
39) Aryal, G.; Battle, C. H.; Grusenmeyer, T. A.; Zhu, M.; Jayawickramarajah, J. A napthalimide derived fluorescence sensor for solid-phase screening of cucurbit[7]uril-guest interactions. Chem Comm. 2016, 52, 2307-2310. DOI: 10.1039/C5CC08350H.
38) Zhu, M.; Zhang, H.; Schmidt, E.; Jayawickramarajah, J. Covalent and Non-covalent Porphyrin-DNA conjugates. In Handbook of Porphyrin Science; Kadish, K.; Smith, K.; Guilard, R. Eds. World Scientific Publishing: Singapore, 2016, Chapter 191, Vol 39, pp 51-81.
37) Su, X.; Zhou, X.; Zhang, N.; Zhu, M.; Zhang, H.; Jayawickramarajah, J. A stable bidentate protein binder achieved via DNA self-assembly driven ligand migration. Chem Comm. 2015, 51,13615-13618. DOI: 10.1039/c5cc03213j.
36) Chu, X.; Battle, C.; Zhang, N.; Aryal, G. H.; Jayawickramarajah, J. Bile acid conjugated DNA chimera that conditionally inhibits carbonic anhydrase-II in the presence of microRNA-21. Bioconjugate Chemistry 2015, 26, 8,1601-1612. DOI:10.1021/acs.bioconjchem.5b00231.
35) Yue, Y.; Qasim, L. N.; Kurnosov, A. A.; Rubtsova, N. I.; Mackin, R. T.; Zhang, H.; Zhang, B.; Zhou, X.; Jayawickramarajah, J.; Burin, A. L.; Rubtsov, I. V. Band-selective energy transport in alkane oligomers: Toward controlling the transport speed. J. Phys. Chem. B. 2015,119, 21, 6448-6456. DOI: 10.1021/acs.jpcb.5b03658.
34) Rubtsova, N.; Nyby, C.; Zhang, H.; Zhang, B.; Zhou, X.; Jayawickramarajah, J.; Burin, A.; Rubtsov, I. Room-temperature ballistic energy transport in molecules with repeating units. J. Chem. Phys. 2015,142, 212412. DOI: 10.1063/1.4916326.
33) Zhu, M.; Aryal, G.; Zhang, N.; Zhang, H.; Schmehl, R.; Liu, X.; Hu, J.; Wei, J.; Jayawickramarajah, J. Host-guest interactions derived multilayer perylene diimide thin film constructed on a scaffolding porphyrin monolayer. Langmuir 2015, 31, 578-586. DOI: 10.1021/la504297w.
32) Zhuang, Y.; Nguyen, H. T.; Burow, M. E.; Zhuo, Y.; El-Dahr, S. S.; Yao, X.; Cao, S.; Flemington, E. K.; Nephew, K. P.; Fang, F.; Collins-Burow, B.; Rhodes, L. V.; Yu, Q.; Jayawickramarajah, J.; Shan, B. Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells. Molecular Carcinogenesis 2015. 54, 12,1656-67. DOI: 10.1002/mc.22237.
31) Loewen, G.; Jayawickramarajah, J.; Shan, B. Functions of LincRNA HOTAIR in lung cancer. J. Hematol. Oncol. 2014, 10. 7, 90-100. DOI: 10.1186/s13045-014-0090-4.
30) Su, X.; Kuang, L.; Battle, C.; Shaner, T.; Mitchell, B. S.; Fink, M. J.; Jayawickramarajah, J. A mild two-step method to construct DNA-conjugated silicon nanoparticles: Scaffolds for the detection of microRNA-21. Bioconjugate Chemistry. 2014, 25, 1739-1743. DOI: 10.1021/bc5004026.
29) Loewen, G.; Zhuo, Y.; Zhuang, Y.; Jayawickramarajah, J.; Shan, B. LincRNA HOTAIR as a novel promoter of cancer progression. J. Cancer Res. Updates 2014, 3 (3), 134-140.
28) Zhang, H.; Zhang, B.; Zhu, M.; Grayson, S.; Schmehl, R.; Jayawickramarajah, J. Water-soluble porphyrin nanospheres: Enhanced photo-physical properties achieved via cyclodextrin driven double self-inclusion, Chem Comm. 2014, 50, 4853-4855. DOI:10.1039/C4CC01372G.
27) Zhang, B.; Zhang, H.; Myers, B. K.; Elupula, R.; Jayawickramarajah, J.; Grayson, S. Determination of polyethylene glycol end group functionalities by combination of selective reactions and characterization by matrix assisted laser desorption/ionization time of flight mass spectrometry. Anal. Chim. Acta. 2014. 816, 28-40.
26) Battle, C.; Chu, X.; Jayawickramarajah, J. Oligonucleotide-based systems for input-controlled and non-covalently regulated protein binding. Supramolecular Chemistry, 2013, 25, 848-862. DOI: 10.1080/10610278.2013.810337.
25) Zhang, N.; Chu, X.; Fathalla, M.; Jayawickramarajah, J. Photonic DNA-chromophore nanowire networks: Harnessing multiple supramolecular assembly modes, Langmuir, 2013, 29, 10796-10806. DOI: 10.1021/la402214p.
24) Lin, Z.; Zhang, N.; Jayawickramarajah, J.; Rubtsov, I. V. Ballistic energy transport along PEG chains: Distance dependence of the transport efficiency. Phys. Chem. Chem. Phys. 2012, 14, 10445-10454.
23) Battle, C.; Jayawickramarajah, J. Supramolecular approaches for inhibition of protein-protein and protein/DNA interactions in Supramolecular Chemistry: From Molecules to Nanomaterials; Steed, J., Gale, P., Eds. John Wiley & Sons Ltd: Chichester, United Kingdom, 2012, pp 1885-1908.
22) Harris, D. C.; Saks, B. R.; Jayawickramarajah, J. Protein-binding molecular switches via host-guest stabilized DNA hairpins. J. Am. Chem. Soc. 2011, 133, 7676-7679. DOI: 10.1021/ja2017366.
21) Mishur, R. J.; Griffin, M. E.; Battle, C. H.; Shan, B.; Jayawickramarajah, J. Molecular recognition and enhancement of aqueous solubility and bioactivity of CD437 by β-cyclodextrin. Bioorg. Med. Chem. Lett. 2011, 21, 857-860.
20) Fathalla, M.; Li, S.-C.; Neuberger, A. Schmehl, R.; Diebold, U.; Jayawickramarajah, J. Straightforward self-assembly of porphyrin nanowires in water: Harnessing adamantane/β-cyclodextrin interactions J. Am. Chem. Soc. 2010, 132, 9966-9967. DOI: 10.1021/ja1030722.
Highlighted in Nature Materials, Aug 2010, Vol. 9, p 605, and is the 8th most-read article in J. Am. Chem Soc. for August 2010.
19) Fathalla, M.; Li, S.-C.; Diebold, U. Alb, A.; Jayawickramarajah, J. Water-soluble nanorods self-assembled via pristine-C60 and porphyrin moieties. Chem Comm. 2009, 4209-4211. DOI: 10.1039/B908050C.
18) Fathalla, M.; Jayawickramarajah, J. Configurational isomers of a stilbene linked bis(porphyrin) tweezer: Synthesis and fullerene binding studies. Eur. J. Org. Chem. 2009, 35, 6095-6099. DOI: 10.1002/ejoc.200901002.
Picked as “Eurbest” article by the editors, and is the one of the most-accessed articles in Eur. J. Org. Chem. for November 2009.
17) Fathalla, M.; Lawrence, C.; Zhang, N.; Sessler, J. L.; Jayawickramarajah, J. Base-pairing mediated non-covalent polymers. Chem. Soc. Rev. 2009. 38, 1608-1620.
16) Harris, D. C.; Chu, X; Jayawickramarajah, J. Protein recognition via oligonucleotide-linked small molecules: Utilization of the hemin-binding aptamer. Supramol. Chem. 2009, 21, 316-323.
15) Harris, D. C.; Chu, X; Jayawickramarajah, J. DNA-small molecule chimera with responsive protein-binding ability.
J. Am. Chem. Soc. 2008, 130, 14950-14951. DOI: 10.1021/ja806552c.
14) Pierce, S. E.; Wang, J.; Jayawickramarajah, J.; Hamilton, A. D.; Brodbelt, J. S. Examination of the effect of the annealing cation on higher order structures containing guanine or isoguanine repeats. Chem. Eur. J. 2009, 15, 11244-11255.
13) Rosenzweig, B. A.; Ross, N. T.; Tagore, D. M.; Jayawickramarajah, J.; Saraogi, l.; Hamilton, A. D. Multivalent protein binding and precipitation by self-assembling molecules on a DNA pentaplex scaffold. J. Am. Chem. Soc. 2009, 131, 5020-5021.
12) Pierce, S. E.; Sherman, C. L.; Jayawickramarajah, J.; Lawrence, C. M.; Sessler, J. L.; Brodbelt, J. S. ESI-MS characterization of a novel pyrrole-inosine nucleoside that interacts with guanine bases. Anal. Chim. Acta. 2008, 627, 129-135.
11) Jayawickramarajah, J.; Tagore, D. M.; Tsou, K.; Hamilton, A. D. Allosteric control of self-assembly: Modulating the formation of guanine quadruplexes through orthogonal aromatic interactions. Angew. Chem. Int. Ed. 2007, 46, 7583-7586. DOI: 10.1002/anie.200701883 (picked as ‘hot-paper’ by the editors)
10) Tagore, D. M.; Sprinz, K. I.; Fletcher, S.; Jayawickramarajah, J.; Hamilton, A. D. Protein recognition and denaturation by self-assembling fragments on a quadruplex scaffold. Angew. Chem. Int. Ed. 2007, 46, 223-225. (picked as ‘hot-paper’ by the editors)
9) Torres, T.; Gouloumis, A.; Sanchez, D.; Jayawickramarajah. J.; Seitz, W.; Guldi, D. M.; Sessler, J. L. Photophysical characterization of a cytidine-guanosine tethered phthalocyanine-fullerene dyad. Chem Comm. 2007, 292-294.
8) Sessler, J. L.; Lawrence, C.; Jayawickramarajah, J. Molecular recognition via base-pairing. Chem. Soc. Rev. 2007, 36, 314-325.
7) Sessler, J. L.; Jayawickramarajah, J.; Gouloumis, A.; Pantos, G. D.; Torres, T.; Guldi, D. M. Guanosine and fullerene derived de-aggregation of a new phthalocyanine-linked cytidine derivative. Tetrahedron 2006, 62, 2123-2131.
6) Sessler, J. L.; Jayawickramarajah, J. Functionalized base-pairs: versatile scaffolds for self-assembly. Chem Comm. 2005, 15, 1939-1949.
5) Sessler, J. L.; Jayawickramarajah, J.; Gouloumis, A.; Torres, T.; Guldi, D. M.; Maldonado, S.; Stevenson, K. J. Synthesis and photophysics of a porphyrin-fullerene dyad assembled through Watson-Crick hydrogen bonding. Chem Comm. 2005, 14, 1892-1894.
4) Sessler, J. L.; Jayawickramarajah, J.; Sherman, C. L.; Brodbelt, J. S. Enhancing Hoogsteen interactions: A pyrrole-containing purine nucleoside that competes with guanosine self-assembly. J. Am. Chem. Soc. 2004, 126, 11460-11461.
3) Sessler, J. L.; Jayawickramarajah, J.; Sathiosatham, M. Energy-and electron-transfer in supramolecular systems. In Encyclopedia of Supramolecular Chemistry; Atwood, J., Steed, J., Eds. Marcel Dekker: New York, 2004, pp 535-545.
2) Sessler, J. L.; Jayawickramarajah, J.; Sathiosatham, M.; Sherman, C. L.; Brodbelt, J. S. A novel guanosine-cytidine dinucleoside that self-assembles into a trimeric supramolecule. Org. Lett. 2003, 5, 2627-2630.
1) Szalai, V. A.; Jayawickramarajah, J.; Thorp, H. H. Electrocatalysis of guanine oxidation in polyethylene glycol solutions: The interplay of adsorption and reaction rate. J. Phys. Chem. B. 2002, 106, 709-716.
