Damir B. Khismatullin

The focus of my laboratory lies in the investigation of the mechanical and transport properties of biomedical systems. Using both computational and experimental approaches, we study the interactions of blood cells and circulating tumor cells with vascular endothelium, explore cavitation effects on the ablation of biological tissues, and develop advanced methods for rheological characterization of living cells and tissues. The clinical applications of this basic research are pathophysiology and treatment of cancer and inflammatory and cardiovascular diseases.

Honors and Awards

NSF-NATO Postdoctoral Fellowship in Science and Engineering (2000-2001)

Selected Publications

http://www.researcherid.com/rid/A-2104-2012

C. Chen and D.B. Khismatullin, “Synergistic effect of histamine and TNF-alpha on monocyte adhesion to vascular endothelial cells,” Inflammation (2012, in press).

P.A. Coghill, E. Kesselhuth, E. Shimp, D.B. Khismatullin, and D.W. Schmidtke, “Effects of microfluidic channel geometry on leukocyte rolling assays,” Biomed. Microdev. (2012, in press).

F. Graziano, V. Russo, W. Wang, D.B. Khismatullin, and A.J. Ulm, “3-D Computational Fluid Dynamics of a Treated Vertebro-Basilar Giant Aneurysm: A Multistage Analysis,” Am. J. Neuroradiol. (2012, in press).

H. Lan and D.B. Khismatullin, “A numerical study of the lateral migration and deformation of drops and leukocytes in a rectangular microchannel,” Int. J. Multiphase Flow 47, 73-84 (2012).

D.B. Khismatullin and G.A. Truskey, “Leukocyte rolling on P-selectin: A 3D numerical study of the effect of cytoplasmic viscosity,” Biophys. J. 102, 1757-1766 (2012).

C. Chen, Y. Liu, S. Maruvada, M. Myers, and D.B. Khismatullin, “Effect of ethanol injection on cavitation and heating of tissues exposed to high intensity focused ultrasound,” Phys. Med. Biol. 57, 937-961 (2012).

W. Wang, B. Meng, D. De Kee, and D.B. Khismatullin, “Optimization of a slotted plate device for low yield stress measurements,” Rheol. Acta 51, 151-162 (2012).

J.C. Chrispell, R. Cortez, D.B. Khismatullin, and L.J. Fauci, “Shape oscillations of a droplet in an Oldroyd-B fluid,” Physica D 240, 1593-1601 (2011).

W. Wang, D. De Kee, and D.B. Khismatullin, “Numerical simulation of power law and yield stress fluid flows in slotted double concentric cylinder and vane geometries” J. Non-Newtonian Fluid Mech. 166, 734-744 (2011).

P.C. Stapor, W. Wang, W.L. Murfee, and D.B. Khismatullin, “The distribution of fluid shear stresses in capillary sprouts” Cardiovas. Eng. Tech. 2, 124-136 (2011).

W. Wang, H. Zhu, D. De Kee, and D.B. Khismatullin, “Numerical investigation of the reduction of wall slip effects for yield stress fluids in a double concentric cylinder rheometer with slotted rotor” J. Rheol. 54, 1267-1283 (2010).

D.B. Khismatullin, “The cytoskeleton and deformability of white blood cells” in Klaus Ley (Ed.), “Current Topics in Membrane. Vol. 64. Leukocyte adhesion”, Birlington: Elsevier/Academic Press, pp. 47-111 (2009).

D.B. Khismatullin, Y. Renardy, and M. Renardy, “Development and implementation of VOF-PROST for 3D viscoelastic liquid-liquid simulations,” J. Non-Newtonian Fluid Mech. 140, 120-131 (2006).

D.B. Khismatullin and G.A. Truskey, “Three-dimensional numerical simulation of receptor-mediated leukocyte adhesion to surfaces: Effects of cell deformability and viscoelasticity,” Phys. Fluids 17, 031505 (2005) (21 pages).

D.B. Khismatullin, “Gas microbubbles and their use in medicine,” in A. Doinikov (Ed.), Bubble and Particle Dynamics in Acoustic Fields: Modern Trends and Applications (Research Signpost, Kerala, India), pp. 231-289 (2005).

D.B. Khismatullin and G.A. Truskey, “A 3D numerical study of the effect of channel height on leukocyte deformation and adhesion in parallel-plate flow chambers,” Microvasc. Res. 68, 188-202 (2004).

D.B. Khismatullin, “Resonance frequency of microbubbles: Effect of viscosity,” J. Acoust. Soc. Am. 116 (3), 1463-1473 (2004).

D.B. Khismatullin, Y. Renardy, and V. Cristini, “Inertia-induced breakup of highly viscous drops subjected to simple shear,” Phys. Fluids 15(5), 1351-1354 (2003).

D.B. Khismatullin and A. Nadim, “Radial oscillations of encapsulated microbubbles in viscoelastic liquids,” Phys. Fluids 14(10), 3534-3557 (2002).

D.B. Khismatullin and I.Sh. Akhatov, “Sound-ultrasound interaction in bubbly fluids: Theory and possible applications,” Phys. Fluids 13, 3582-3598 (2001).

D.B. Khismatullin and A. Nadim, “Shape oscillations of a viscoelastic drop,” Phys. Rev. E 63, 061508 (2001) (10 pages).