Mark Mondrinos
Assistant Professor of Biomedical Engineering
Office
Uptown: 536 Lindy Boggs Center
Downtown: 413 J. Bennett Johnston Building
Department of Biomedical Engineering
Tulane University New Orleans, LA 70118
Courses Taught
Fall
BMEN 6440: Microphysiological Systems
Spring
BMEN 3070/6070: Quantitative Physiology
Education & Affiliations
Biography
Research Interests
Our laboratory engineers biologically-inspired microphysiological systems and organoid-based models of human tissues and organs including the lungs, skeletal muscle and organ-specific interstitial tissues. We utilize confocal microscopy and rigorous biochemical analysis to study normal physiological functions and disease states in these models, with a strong emphasis on filling the translational gap to accelerate preclinical screening of novel therapeutic paradigms. Currently, we are working to build models of respiratory exposure injury (i.e. smoking, vaping, environmental exposures), inflammatory and fibrotic disorders of the interstitium in various organ contexts, and muscle tissue injury. An exciting area of focus is engineering multi-organ microfluidic models to study the systemic effects of malignancy (i.e. Cachexia) and screen palliative therapies that will improve quality of life in patients with incurable disease.
Honors and Awards
Jeanette Piperno Memorial Award, Sol Sherry Thrombosis Research Center, Temple University School of Medicine, 2013.
Best PhD Dissertation in the Physical and Life Sciences, Drexel University, 2011.
