Mark Mondrinos

Assistant Professor of Biomedical Engineering

(504) 865-5854
School of Science & Engineering


Uptown: 536 Lindy Boggs Center
Downtown: 413 J. Bennett Johnston Building
Department of Biomedical Engineering
Tulane University New Orleans, LA 70118

Courses Taught

BMEN 3400/6400: Biomaterials & Tissue Engr

BMEN 3401/6401: Biomaterials & Tissue Engr Lab

BMEN 3070/6070: Quantitative Physiology

Education & Affiliations

Center for Engineering Mechanobiology at Penn; Inaugural Fellow, 2017
The University of Pennsylvania (with Prof. Dan Huh); Postdoctoral Fellow, Bioengineering, 2014-2016
Temple University School of Medicine (with Prof. Laurie Kilpatrick); Postdoctoral Fellow, Center for Inflammation and Lung Research, 2012-2014
Drexel University, Philadelphia, PA. 2011. Ph.D. in Biomedical Engineering
Florida State University, Tallahassee, FL. 2002. B.Sc. Chemical Engineering; B.Sc. Biological Chemistry


Research Interests

Our laboratory engineers biologically-inspired microphysiological systems and organoid-based models of human tissues and organs including the lungs, skeletal muscle and organ-specific interstitial tissues. We utilize confocal microscopy and rigorous biochemical analysis to study normal physiological functions and disease states in these models, with a strong emphasis on filling the translational gap to accelerate preclinical screening of novel therapeutic paradigms. Currently, we are working to build models of respiratory exposure injury (i.e. smoking, vaping, environmental exposures), inflammatory and fibrotic disorders of the interstitium in various organ contexts, and muscle tissue injury. An exciting area of focus is engineering multi-organ microfluidic models to study the systemic effects of malignancy (i.e. Cachexia) and screen palliative therapies that will improve quality of life in patients with incurable disease.

Honors and Awards

Jeanette Piperno Memorial Award, Sol Sherry Thrombosis Research Center, Temple University School of Medicine, 2013.
Best PhD Dissertation in the Physical and Life Sciences, Drexel University, 2011.

Journal Articles