Education

Ph.D., 1981, Michigan State University

Biography

Dr. Dohanich and his students have studied the influences of ovarian and adrenal steroids and biological sex on behavior. Employing a rodent model, early work focused on the interaction of estrogen and acetylcholine in mediating reproductive behaviors.  Subsequent projects investigated the interaction of estrogen and acetylcholine in modulating learning and memory.  More recent studies explored the expression and development of sex differences in learning and behavior, and their relationship to anxiety.

Dr. Dohanich no longer mentors graduate or undergraduate students in his laboratory, and now concentrates his efforts on educational activities that include offering new graduate and undergraduate courses and expanding his teaching methodologies.

Selected Publications

Grissom, E.M., W.R. Hawley, and G.P Dohanich. Organizational effects of testosterone on learning strategy preference and muscarinic receptor binding in prepubertal rats. Hormones and Behavior 110:1-9, 2019. https://www.sciencedirect.com/science/article/pii/S0018506X18304215 

Nahar, J., J. R. Rainville, G. P. Dohanich, and J. G. Tasker. Further evidence for a membrane receptor that binds glucocorticoids in the rodent hypothalamus. Steroids, 2016.  http://www.ncbi.nlm.nih.gov/pubmed/27327842

Mueller, S. C., E. M. Grissom, and G. P. Dohanich. Assessing gonadal hormone contributions to affective psychopathologies across humans and animal models.  Psychoneuroendocrinology 46:114-128, 2014.
http://www.ncbi.nlm.nih.gov/pubmed/24882164

Serefoglu, E. C., W. R. Hawley, G. F. Lasker, E. M. Grissom, S. H. Mandava, S. C. Sikka, G. P. Dohanich, and W. J. Hellstrom.  Effect of botulinum-A toxin injection into bulbospongiosus muscle on ejaculation latency in male rats. Journal of Sexual Medicine 11:1657-1663, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24774776

Cost, K. T., T. D. Lobell, Z. N. Williams-Yee, S. Henderson, and G. Dohanich.  The effects of pregnancy, lactation, and primiparity on object-in-place memory of female rats. Hormones and Behavior 65:32-39, 2014.
http://www.ncbi.nlm.nih.gov/pubmed/24211441

Ferland, C. L., W. R. Hawley, R. E. Puckett, K. Wineberg, F. D. Lubin, G. P. Dohanich, and  L. A. Schrader.  Sirtuin activity in dentate gyrus contributes to chronic stress-induced behavior and extracellular signal-regulated protein kinases 1 and 2 cascade changes in the hippocampus.  Biological Psychiatry 74:927-935, 2013.
http://www.ncbi.nlm.nih.gov/pubmed/24011821

Hawley, W. R., E. M. Grissom, J. M. Patel, K. S. Hodges, and G. P. Dohanich.  Reactivation of an aversive memory modulates learning strategy preference in male rats.  Stress, 73-86, 2013. 
http://www.ncbi.nlm.nih.gov/pubmed/22533611

Hawley, W. R, E. M. Grissom, R. C. Martin, M. B. Halmos, C. L. Bart, and G. P. Dohanich.  Testosterone modulates spatial recognition memory in male rats.  Hormones and Behavior 63:559-565, 2013.
http://www.ncbi.nlm.nih.gov/pubmed/23481590

Grissom, E. M., W. R. Hawley, K. S. Hodges, J. M. Fawcett-Patel, and G. P. Dohanich.  Biological sex influences learning strategy preference and muscarinic receptor binding in specific brain regions of prepubertal rats. Hippocampus 23:313-322, 2013.
http://www.ncbi.nlm.nih.gov/pubmed/23280785

Grissom, E. M., W. R. Hawley, S. S. Bromley-Dulfano, S. E. Marino, N. G. Stathopoulos, and G. P. Dohanich.  Learning strategy is influenced by trait anxiety and early rearing conditions in prepubertal male, but not prepubertal female rats.  Neurobiology of Learning and Memory 98:174-181, 2012.
http://www.ncbi.nlm.nih.gov/pubmed/22705447

Cost, K. T., Z. N. Williams-Yee, J. N. Fustok, and G. P. Dohanich.    Sex differences in object-in-place memory in adult rats.  Behavioral Neuroscience 126:457-464, 2012.
http://www.ncbi.nlm.nih.gov/pubmed/22642887

Hawley, W. R., E. M. Grissom, H. E. Barratt, T. S. Conrad, and G. P. Dohanich. The effects of biological sex and gonadal hormones on learning strategy in adult rats.  Physiology and Behavior 105:1014–1020, 2012.
http://www.ncbi.nlm.nih.gov/pubmed/22146478

Hawley, W.R., E.M. Grissom, and G.P. Dohanich. The relationships between trait anxiety, place recognition memory, and learning strategy. Behavioural Brain Research 216:525–530, 2011.
http://www.ncbi.nlm.nih.gov/pubmed/20801159

Hawley, W., E. Grissom, L. Keskitalo, T. Hastings, and G. Dohanich. Sexual motivation and anxiety-like behaviors of male rats after exposure to a trauma followed by situational reminders. Physiology and Behavior 102:181–187, 2011.
http://www.ncbi.nlm.nih.gov/pubmed/21044642

Frankola, K.A, A.L. Flora, A.K. Torres, E.M. Grissom, S. Overstreet, and G P. Dohanich.  Effects of early rearing conditions on cognitive performance in prepubescent male and female rats. Neurobiology of Learning and Memory 94:91-99, 2010.
http://www.ncbi.nlm.nih.gov/pubmed/20403447

Tunur, T., G.P. Dohanich, and L.A.Schrader.  Pre-exposure to context affects learning strategy in mice. Learning and Memory 17:328-331, 2010.
http://www.ncbi.nlm.nih.gov/pubmed/20573774

Dohanich, G.P., D.L. Korol, and T. Shors. Steroids, learning and memory.  In Hormones, Brain and Behavior, (Second Edition, Vol. 1), edited by D. W. Pfaff, A. P. Arnold, A, M. Etgen, S. E. Fahrbach, and R. T. Rubin. San Diego: Academic Press, pp. 539-576, 2009.

Luine, V.N. and G.P. Dohanich. Sex differences in cognitive function in rodents.  In Sex Difference in the Brain: From Genes to Behavior, edited by J. Becker et al., Oxford University Press, pp. 227-251, 2008.

Directed Ph.D. Dissertations

Robert Hunter – Uric acid and adenosine binding in young rats: A model of hyperactivity (1987)

Cheryl Menard– Estrogen-dependent cholinergic regulation of sexual receptivity in intact cycling female rats (1991)  (Associate Professor and Head of Psychology, University of Louisiana at Lafayette)

Thomas Hebert – Gonadal steroid regulation of NADPH-diaphorase histochemistry in the male and female rat brain (1996)  (Senior Professor of Practice of Psychology, Tulane University)

Aric Fader – The effects of estrogen delivered to the medial preoptic area and hippocampal formation on spatial performance in a radial arm maze (2000)  (Senior Medical Writer, MedVal Scientific)

Jill Daniel – The role of acetylcholine in the estrogen-induced increase in hippocampal NMDA receptor binding and in the associated enhancement of working memory performance (2000)  (Professor of Psychology and Director of the Tulane Brain Institute, Tulane University)

Barry Row – Role of corticotropin-releasing hormone in the modulation of spatial memory (1999)  (Assistant Professor, University of Louisville)

Zuzana Hruska – Effects of estrogen treatment on working memory impairments induced by beta-amyloid and ibotenic acid in female rats (2003)   (Faculty, Geosystems Research Institute)

Wayne Hawley – Modulation of spatial cognition in adult rats by biological sex, gonadal steroids, affective conditions, and cholinergic neurotransmission (2013)   (Associate Professor, Department of Psychology, Edinboro University)

Elin Grissom – The relationships between sex differences in learning strategy in early life and neurochemical and neuroarchitectural endpoints in multiple memory systems (2013)  (Associate Professor, Department of Psychology, Loyola University of New Orleans)

Katherine Cost – Spatial ability during pregnancy and motherhood in rats and humans: A comparative study (2013)  (Postdoctoral Fellow, Department of Psychology, University of Toronto)

Directed M.S. Theses

Nonnie Estrella
Jill Daniel
Aric Fader
Gregory Dillon
Laura Bolton
Peter Peloquin
Amanda Crawford Torres
Jonathan Santoro
Kelly Hodges
Thomas Lobell